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In addition to activating PKGI, cGMP itself contributes to smooth muscle relaxation through direct inhibition of the plasma membrane localized L-type Ca 2+ channels

Anti-inflammatory cytokine expression: The peptide shifts cytokine profiles toward anti-inflammatory patterns, reducing chronic inflammation that impedes healing

FUT2 (the "secretor" gene, variant rs602662) is one of the strongest common genetic determinants of circulating B12 levels

The iron chelators Dp44mT and DFO inhibit TGF--induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1)