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The REDEFINE 1 and REDEFINE 2 Phase 3 trials used a once-weekly subcutaneous dose of cagrilintide 2.4 mg combined with semaglutide 2.4 mg, reached after roughly 16 weeks of dose titration

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"If there is another wave of publicity," Gates warned, "the FDA might be compelled to reconsider the matter and require a specific warning regarding a possible risk of toxicity in chronic alcohol abusers." Gates, long retired from McNeil, was too ill to respond to questions, his wife said

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