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High bioavailability

Reimbursement expansion across the 47-country access market is estimated to add USD 28.4 billion to the global GLP-1 market through 2030

40% of surveyed doctors agree that a government-backed site can maintain objectivity

CVOTs cardiovascular outcome trials, T2DM type 2 diabetes mellitus, CVD cardiovascular disease, HF heart failure, CKD chronic kidney disease, HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, GLP-1R GLP-1 receptor, T1DM type 1 diabetes mellitus, GLP-1RAs glucagon-like peptide-1 receptor agonists, DPP-4i DPP-4 inhibitor, HR hazard ratio, CI confidence interval Except for ELIXA and EXSCEL [56, 59], all other major CVOTs point towards cardiovascular benefits of GLP-1RAs [53, 54, 61, 63, 6668]

GHRP-2 (pralmorelin) is slightly more potent on GH (~16 baseline), less orexigenic, but maintains a dose-dependent increase in cortisol (+20-40%) and prolactin (+15-30%)