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(PubMed) FitzGerald JD

Experimental studies suggest that the peptide may influence the secretion of hormones, and a possible mechanism of action involving the modulation of adrenergic transmission has been proposed

Importantly, these analyses did not explore differential effects based on age, sex, and race/ethnicity of trial participants, so a high-risk subpopulation cannot be excluded

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This is why medical literature consistently shows that weight loss gains fade when patients discontinue GLP-1 therapy without lifestyle modifications in place