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This schematic diagram explains several underlying principles and potential roles of garlic bioactives for hypertension management involving elicitation of NO bioavailability, enhancement of H2S production and CSE activity, inhibition of ACE and reduction of proliferation and migration of vascular smooth muscle cells

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However, when there is an imbalance in the adrenal hormones, this delicate balance is disturbed, which results in increased ROS generation and reduced antioxidant defences (5)

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