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Proteins downregulated by GLP-1GIPLani (cluster 1) were mainly associated with calcium and tubulin binding, ion channel and phosphatase regulation and protein folding, whereas proteins upregulated by GLP-1GIPLani (cluster 3) were linked to oxidative and lipid metabolism, ribosomal activity and amino acid and carbohydrate metabolism (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Liang L., Gu X., Zhao J.Y., Wu S., Miao X., Xiao J., Mo K., Zhang J., Lutz B.M., Bekker A., et al

However, translating these concepts into market-ready products requires careful navigation of an evolving and fragmented regulatory landscape