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CS is the primary cause of chronic obstructive pulmonary disease (COPD), with as much as 90% of COPD patients having been smokers at one point in their lifetime [5, 6]

Improves bone health and prevents bone diseases Vitamin B12 is essential for the proper deposition of minerals in the bone and hence for maintaining the normal density of the bone

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Ethics declarations Competing interests The author declares associations with the following companies: Astra-Zeneca, Bristol-Myers Squibb, Merck Sharpe & Dohme, NovoNordisk and Sanofi-Aventis (advisory board membership