semaglutide studies and Cardiovascular Outcomes in Obesity without Diabetes Semaglutide and Type 2 Diabetes

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Tirzepatide showed significantly lower rates and no signal above background.[7] A post-hoc analysis of the SURMOUNT trials published in 2026 found tirzepatide had favorable psychiatric safety overall.[8] These are pharmacovigilance signals, not proof of causation

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As a neurologist deeply invested in the evolving landscape of medicine, I find the recent publication by Porcari and colleagues in Cell both timely and one day may be transformative