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In 2022, SAR441255 (GLP-1/GIP/glucagon receptor triagonist) was administered to obese, diabetic primates and healthy lean to overweight humans without diabetes

Am J Clin Nutr 68(2):447S-463S

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For those with a history of disordered eating, the medications success (strong appetite blunting) may mask relapseskipping meals, obsessing over the scale, or overtraining to maximize weight loss