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Emotional Blunting and Mental Fatigue Some people describe feeling: Flat Unmotivated Disconnected Mentally drained This can be a sign that the medication is over-regulating dopamine , leading to emotional and cognitive fatigue rather than clarity

Clearly this area needs further research to find out if its causative or not." James Hewes, a Bristol consultant surgeon who also specialises in obesity and bariatric surgery, also told the BBC: "Anecdotally, we are seeing more patients presenting with gallstones

Postmenopausal women and men with PDE5-nonresponsive erectile dysfunction are the two off-label groups most often discussed

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