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Bahnson JL, Knowler WC, Bantle JP, Bertoni AG, Bray GA, Chen H et al (2014) Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial

Start 0.10.5% , commonly up to 2%

Body weight may influence dosing for some compounds, especially weight-based dosing tied to certain FDA-approved indications

One of the primary uses of acetyl-L-carnitine is to treat neurodegenerative diseases such as Alzheimer's, and there is evidence to suggest it can also be used to treat symptoms of depression, improve brain function, and reduce fatigue (3)

You are in a pharmacological valley where neither medication provides its maximum effect