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Similarly, elevated global DNA methylation, Dnmt activity, and 5-methylcytosine but decreased Tet activity and 5-hydroxymethylcytosine were observed in the GSH-deficient hepatocytes and the liver of HFD-fed mice
doi: 10.1007/s10072-015-2318-7
The amino acid residues that make up the H-site are involved in recognizing and binding various exogenous and endogenous compounds and positioning their electrophilic centers for attack by the nucleophilic GSH
Nutrients (2023) 15:743
As a shield, glutathione absorbs the damage and prevents oxidation of the nearby cell components
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