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This aligns with our research, underscoring the enhancement of mitochondrial function through mitophagy under hypoxic conditions

Biochem Pharmacol 39:5965 Schnleben-Janas A, Kirsch P, Mittl PR, Schirmer RH, Krauth-Siegel RL (1996) Inhibition of human glutathione reductase by 10-arylisoalloxazines: crystalline, kinetic, and electrochemical studies

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Targeting the Src homology 2 (SH2) domain of signal transducer and activator of transcription 6 (STAT6) with cell-permeable, phosphatase-stable phosphopeptide mimics potently inhibits Tyr641 phosphorylation and transcriptional activity

All one carbon metabolism (methylation) reactions occur within mitochondria