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Saini RK, Prasad P, Lokesh V, Shang X, Shin J, Keum YS, et al

This promoter is active in neural crest cells, and driving MYCN overexpression in these progenitor cells of NB causes the animals (Th- MYCN ) to develop tumors that closely resemble human NB ( in vitro

To gain insights into the mechanism of VERO cell toxicity at high compound concentrations, the compounds were tested for inhibition of human cytoplasmic TrxR1 and GR

(137) further indicated that DKD microvascular complications are closely associated with abnormal BCAA metabolism, with high levels of L-leucine [area under the curve (AUC) = 0.834] and isoleucine (AUC = 0.932) demonstrating high diagnostic ability in distinguishing DKD from T2DM