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Across these trials, tesamorelin at 2 mg subcutaneously once daily produced a statistically significant reduction in visceral adipose tissue and waist circumference over 26 weeks, with 26-week extension phases showing that the visceral-fat improvement was maintained on continued treatment and, importantly, without adverse effects on blood glucose or lipid parameters in those analyses

Supplementary Table 5 Complete list of kidney outcomes assessed

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Hydration is extra important on GLP-1s because some people drink less when they feel less hungry