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Mitochondrial targeting of antioxidants alters pancreatic acinar cell bioenergetics and determines cell fate

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LDH inhibitors and dichloroacetate can reduce lactate production [131, 132], while MCT1/MCT4 inhibitors reshape lactate gradients and acidity in the TME [133, 134]

In preclinical models, BPC-157 accelerates angiogenesis in tendons, ligaments, muscles, and the GI tract