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The 3 month lag was introduced for clinical and long-term outcomes to allow for an adequate amount of time to achieve some meaningful efficacy

After an overnight fasting, an upper abdominal midline incision was made under anesthesia (100 mg/kg ketamine and 10 mg/kg xylazine, intraperitoneally, i.p.)

Xie Y, Hou W, Song X, Yu Y, Huang J, Sun X et al (2016) Ferroptosis: process and function

In: Inze D, Van Montagu M (eds) Oxidative Stress in Plants

One important caveat is that starting minoxidil can itself cause a brief period of increased shedding during the first two to four weeks, as it pushes telogen hairs out to make room for new anagen hairs