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Baggio L.L., Drucker D.J

Moreover, these agents also reduced the total amount of time spent in the hospital or intensive-care unit and the duration of antibiotic therapy use [75]

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The former seeks to decrease plasma levels of Lp(a) by causing apo(a) mRNA degradation, blocking apo(a) synthesis in the liver, and reducing Lp(a) secretion in particular [219], while the latter accomplishes the same goal by reducing Lp(a) levels through inhibiting the translation of the LPA gene's mRNA in hepatocytes and mutating the causing gene [232]

doi: 10.1371/JOURNAL.PONE.0256998 120 BaiFTomasoniDFalcinellaCBarbanottiDCastoldiRMulGet al