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In an announcement on Thursday the Medicines and Healthcare products Regulatory Agency (MHRA) approved the UKs first GLP-1 receptor agonist tablet for weight loss and weight management

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NICE first recommended the drug in draft guidance 2022, after a clinical trial of just under 2000 volunteers found that people lost on average 12% more weight with semaglutide alongside supervised weight loss coaching (BMJ 2023;380:556)

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Program details cited in this release are published here: View the current SynergyRx GLP-1 offer (official SynergyRx page)

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RYBELSUS is not approved for subcutaneous use

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The benefits of Rybelsus for diabetes management, as demonstrated in clinical trials, generally outweigh temporary digestive discomfort for most patients

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