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These are uncomfortable but generally manageable if dosing is monitored

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The GIP component supports healthy fat cell expansion, which prevents ectopic fat spillover into visceral depots and organs

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There are also quality and sourcing concerns, as peptides obtained from unregulated sources may be mislabeled, contaminated, or falsified, which increases risks

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The primary composite outcome of major adverse cardiac events plus (MACE+), including death from CV causes, nonfatal MI, and hospitalization for unstable angina, was reached in 13.4% of patients in the lixisenatide group and 13.2% of patients in placebo group, demonstrating noninferiority, but not superiority, of lixisenatide compared with placebo

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GLP-1s improve systemic metabolic function, which can lower inflammation and improve overall health

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