By mimicking GLP-1, Semaglutide: Increases the production of insulin (which lowers blood sugar) Decreases the production of glucagon (which raises blood sugar) More importantly, it slows down gastric emptying the rate at which food leaves the stomach
Efficacy Although there are no head-to-head trials comparing Mounjaro to Wegovy, there was a trial comparing Mounjaro to Ozempic
Like other GLP-1-style medications, the most common side effects have been gastrointestinal, including nausea, diarrhea, constipation, and vomiting
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they work opposite of each other so that blood sugar decreases during and right after meals (thanks to insulin), and levels increase between meals, giving the body steady energy levels (due to glucagon)