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The SELECT, STEP, and ESSENCE programs collectively support its role across this spectrum, with robust efficacy but a characteristic GLP1 RA tolerability profile that necessitates careful initiation, titration, and monitoring

This will lead to an increase in belly fat and waist circumference

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As a precaution, these drugs are typically not prescribed to individuals with a personal or family history of medullary thyroid carcinoma or those with Multiple Endocrine Neoplasia syndrome type 2