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[DOI] [PMC free article] [PubMed] [Google Scholar] 132.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Vranes H., Knezevic T., Barisic I., Horvat Pavlov K., et al
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Adipocyte Metabolism and Function Research Laboratory studies investigate AOD9604s effects on adipocyte biology: Lipogenesis Inhibition: Examination of de novo lipogenesis suppression, ACC inhibition, FAS expression Fatty Acid Oxidation: Research on -oxidation enhancement, CPT1 activity, mitochondrial function Adipocyte Differentiation: Studies on preadipocyte differentiation, PPAR expression, adipogenesis Metabolic Gene Expression: Investigation of transcriptional programs affecting lipid metabolism Inflammatory Markers: Research on cytokine expression, macrophage infiltration, inflammatory signaling Experimental models include 3T3-L1 adipocyte differentiation, primary adipocyte cultures, and adipose tissue explants
FDAs Concerns With Unapproved GLP-1 Drugs Used for Weight Loss
