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For patients aged 50 years and older, recommended screening should include age-appropriate investigations in accordance with prevailing clinical practice guidelinessuch as colonoscopy for colorectal cancer, mammography for breast cancer, and cervical cytology or HPV testing as indicated

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Cancer-type oatp1b3-V1 is a functional plasma membrane transporter mediating increased uptake of chemotherapeutics in vitro and in vivo

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Accordingly, in mice, IL-17A and IL-17C can activate basolateral amygdala neurons with IL-17 receptor A, promoting anxiety-like behaviors, whereas IL-10 opposes this pathway