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Translationally, incorporation of omega-3 fatty acids and dietary oils into the context of breast cancer treatment require a precision nutrition approach based on natural production vs mimicking chemical derivatives for clinical practice, supplements with standardized formulas containing optimal ratios of EPA/DHA, advanced delivery methods such as nanoemulsions that increase bioavailability, multicentre randomized controlled trial studies (ideally large-scale) focusing thematically on meaningful endpoints related to clinical outcomes including OS and RFS (172)

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