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DOI: 10.1016/j.ajcnut.2022.11.007 56
Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)
Over the past four seasons, 100% of our playwrights and 97% of our creative teams have been artists of historically excluded genders
Glutaminase inhibitors inhibit pyrimidine synthesis and increase the ROS level in VHL-deficient RCC cells, and the PARP inhibitor olaparib and glutaminase inhibitors synergically inhibit the growth of these cells in vivo and in vitro (58)
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