Occasional nausea is common with GLP-1 RAs, but persistent vomiting (GLP-1 related or not) can deplete electrolytes significantly.Hyponatremia and hypernatremia (sodium imbalance)Sodium abnormalities typically only occur when significant vomiting, diarrhea, dehydration, or excessive water intake accompany GLP-1 RA use."Sodium can trend low (hyponatremia) if large amounts of free water are consumed without adequate electrolytes, or high (hypernatremia) if fluid intake is inadequate," Dr
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Kelly, S
Guidance on clinical review is provided in the document and clinicians are referred to NICE Guideline 28 Type 2 diabetes in adults: management
GLP-1 medications are not appropriate for everyone, and the safest plan depends on the patients medical history, current medications, goals, lab markers, and risk factors
