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While not approved to treat these conditions, in a clinical trial, people who dieted, exercised and took Zepbound for the treatment of obesity or overweight with weight-related medical problems observed changes in cholesterol and reductions in blood pressure and waist size

11 While this is a rare adverse effect (ranging from one in 1,000 to one in 3,000 people), this should be discussed with patients before initiating treatment, with advice provided on the symptoms and signs of DKA and when to seek medical attention to get their blood ketones checked (i.e

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By combining all three receptor signals, triple agonists aim to reduce appetite (GLP1 and GIP), increase caloric burn (glucagon), and improve liver fat metabolism (glucagon)