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By subcutaneous injection

2006;34(PT 2):330-333

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They observed that compared to the controls, the total antioxidant status was decreased, total oxidant status was increased, and markers of apoptosislike PARP-1 and Caspase-3 were elevated in the CBZ-treated group, leading to their conclusion that renal toxicity due to CBZ treatment occurs through oxidative stress-mediated apoptosis 19