Their positive impact is mainly due to the blending of bio-friendly and synthetic elements in hybrid NPs tested in preclinical and clinical settings for wound healing applications
Although, short term depletion of mucosal GSH per se by diethylmaleate did not result in mucosal injury, the oral administration of NAC (40 mm) 4 hours after TNBS+ethanol treatment increased GSH stores (2fold), decreasing the extent of mucosal injury (6070%) examined at 24 hours post treatment
In addition, the antioxidant activity of AST was preserved by SSLNs as confirmed by oxygen radical absorbance capacity (ORAC) assay (Table 1)
Zhang H, Yue X, Chen Z, Liu C, Wu W, Zhang N, et al
Genetic polymorphisms of glutathione S -transferase genes GSTM1 GSTT1 and risk of hepatocellular carcinoma