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Preclinical studies have shown that melittin and crude BV exert strong anti-metastatic and cytotoxic effects against various tumor cells, including breast, lung, prostate, and liver cancer cell lines [13]

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6.8 Menopause and Skin Changes Post menopause, there is a rapid decline in the macroscopic and histological appearance of the skin with an increase in wrinkling, sagging and dryness [78, 79] (Fig

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