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Glutathione is the most prominent antioxidant in the retina and a depletion has been shown to be involved in a number of different types of retinal cell death, as well as stress-induced premature senescence

No: HR-POK-007

GPx7 likes to interact with the domain of PDI, and intramolecular cooperation between the two redox-active sites of PDI increases the activity of the Ero1/GPx7/PDI triplet, thereby promoting protein folding mechanisms (Wang et al., 2014) (Figure 6)

The 2026 edition became effective October 1, 2025, under the standard annual ICD-10-CM update cycle maintained by NCHS