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Oncogene 17, 30453054

So, rather than focus on just the subjective nature of pain, let's talk about the absolute qualities of pain, and the absolute qualities of pleasure, so that we can learn how to navigate those two experiences in ways that serve us each better

Heery JM, Kozak M, Stafforini DM, Jones DA, Zimmerman GA, McIntyre TM, Prescott SM

Hagen, Ph.D

For example, interleukin-1, which triggers cell activation by binding to specific membrane receptors, plays a key role in initiating an inflammatory cascade, but interleukin-10, produced by microglia and astrocytes and lymphopoietic cells, appears to play a neuroprotective role by producing anti-inflammatory cytokines