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Given TB-500s pleiotropic biology across multiple tissue types and cell populations, peptide impurities could introduce confounding biological signals across the broad range of assay systems in which TB-500 is studied , making high purity verification particularly important for research designs involving multiple endpoints or comparative studies

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Arch Toxicol 96:23912417 Alim I, Caulfield JT, Chen Y, Swarup V, Geschwind DH, Ivanova E et al (2019) Selenium drives a transcriptional adaptive program to block ferroptosis and treat stroke

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