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These findings suggest that reduced levels of this antioxidant may be involved in the pathophysiology of major depressive disorder, and may prove a promising drug target (Maes et al

Mild deficiency: Patients with mild B12 deficiency might only need a small dose

Always inform your physician or qualified healthcare professional about any dietary supplements or nonprescription products you are using

Some researcher communities report using oral or sublingual routes

Notably, nuciferine, the primary bioactive compound isolated from lotus leaf, can prevent iron accumulation and lipid peroxidation in folic acid-induced AKI by enhancing intracellular GSH and GPX4 levels, ultimately inhibiting ferroptosis (166)