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Moreover, given that up to 50% of people are estimated to regain weight after discontinuing treatment in real world settings, preserving muscle mass with exercise rather than the usual fat led regain may be of particular interest.418 Finally, for adverse events that are more difficult to study because of their low incidence (eg, NAION), patients need to be advised of the small but still clinically significant risk with use of the GLP-1 receptor agonists

This recent review describes the range of hepatic manifestations observed in patients with WD