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Chehelgerdi M, Chehelgerdi M, Allela OQB, Pecho RDC, Jayasankar N, Rao DP, et al

It has been shown that L-glutamine stimulates GLP-1 secretion by activating Gs through Gs-coupled receptors like taste receptor type 1 member 3 (TAS1R3) in intestinal L-cells 28

Moreover, demonstrating clear cardiovascular risk reduction is assisting manufacturers in securing better insurance reimbursements and payer coverage, making these historically expensive treatments more accessible to the public

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Finally, the PLB dosage and administration strategy should be refined, and its long-term effects and potential side effects should be comprehensively evaluated to confirm its safety and effectiveness in clinical applications