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The pathophysiology of unexplained infertility remains unclear

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W badaniach in vitro wykazano, e aktywacja receptora MC1R stymuluje szlak cAMP/PKA w melanocytach, co prowadzi do fosforylacji CREB i aktywacji transkrypcji genw zwizanych z melanogenez (tyrozynaza, TRP-1, TRP-2)

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