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Total weekly receptor exposure stays the same

Normalization of circadian rhythm stabilizes melatonin secretion, improving sleep quality and nighttime regeneration

The authors were clear that stronger evidence is needed before GLP-1 drugs are seriously considered for infections, dementia or other non-cardiometabolic uses

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Based on the results of these clinical trials, Novo Nordisk submitted a new drug application for Semaglutide to the US Food and Drug Administration (FDA) in 2017 and was approved for marketing at the end of 2017