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Trials like EMPAREG OUTCOME and REWIND underscore how newer medications reshape risk management, leading some experts to recommend earlier initiation of these agents in patients with elevated cardiovascular or renal risks

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Anti-Inflammatory Effects: Systemic inflammation reduction by decreasing pro-inflammatory cytokines like TNF- 3/ Possible Chronic Disease Risk Reduction Cardiovascular Health: semaglutide a GLP-1-RA has shown promise of lifespan extension in obese individuals by reducing the risk of cardiovascular disease

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