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It's important to talk honestly with your healthcare provider

There are many potential processes underlying MTX toxicity (Reference Chan and Cronstein33) , but no effective treatments to ameliorate the condition exist

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Primarily in the intestines, we house an estimated 38 trillion microbes (Sender et al., 2016), among which at least 2,172 known species (Hugon et al., 2015), comprising about as many (small) microbial cells as we have (large) human ones (Sender et al., 2016)