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5 About the SELECT Trial SELECT (Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity) was a multicenter, randomized, double-blind, placebo-controlled, event-driven superiority trial designed to evaluate the efficacy of Wegovy 2.4 mg versus placebo as an adjunct to cardiovascular standard of care for reducing the risk of major adverse cardiovascular events in people with established CVD with overweight or obesity with no prior history of diabetes

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Although compounders can no longer produce copies of these weight loss drugs, there is definitely a chance that the med spas and telehealth companies that sell these drugs may continue to (or pivot to) offer custom compounded options by offering specialized dosages or combining them with vitamins, says DiStefano

Retatrutide has exploded in popularity since Eli Lilly published Phase 2 trial data showing up to 24.2% body weight reduction over 48 weeks