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GLP-1Rs is present in many tissues, suggesting that their widespread physiological functions beyond glycemic control could potentially include, for example, neuroprotective, anti-inflammatory, and cardioprotective activity [13]

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The upregulation of the tumour suppressor gene P53 leads to the accumulation of lipid hydroperoxides by inhibiting the expression of SLC7A11 and reducing the level of GSH, eventually triggering ferroptosis [81]

doi:10.1001/jama.2009.1622 [10] Arakawa Y, Watanabe M, Inoue N, et al