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Addressing these knowledge gaps will be essential in translating the scientific promise of PSYs into viable, evidence-based therapies for people living with MS (Figure 2)

Introduction The histopathological diagnosis and classification of melanocytic skin tumors is probably the greatest conceptual and practical challenge in modern dermatopathology and is expected to rapidly evolve in the next future, with the WHO 2018 classification being the basis for the forthcoming studies ( Table 1 )

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Beyond sleep, DSIP is investigated for its effects on stress adaptation, pain modulation, and neuroendocrine regulation, including potential interactions with cortisol, melatonin, and growth hormone pathways