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While treatment strategies for AD have principally targeted individual pathological hallmarks such as amyloid and tau with limited success in modifying the disease course, to have an effective disease-modifying treatment it may be necessary to target multiple pathologies [8, 9]
S., Scheunemann, V., Gruedl, S., Oezkabakcioglu, Y., Poppe, E., & Petersohn, D
Dahlin, M
POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )
ensuring faster repair and anti-inflammatory effects
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