Eli Lilly's latest data release follows the company's earlier findings, released in early August, that showed that trial participants who are overweight or have obesity lost an average of 27 pounds or about 12.4% of their body weight after taking Eli Lilly's oral daily GLP-1 pill -- orforglipron -- for at least 72 weeks
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Moreover, the inconvenience and discomfort associated with subcutaneous injection could negatively impact medication adherence ( Oral formulations of GLP-1 RAs enhance treatment convenience, acceptance, and adherence, offering patients an alternative option to achieve glycemic goals without injections (Thethi et al., 2020)