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Proposed mechanisms include autonomic nervous system modulation and potential direct cardiac effects via GLP-1 receptors

And HO-1 related to programmed cell death such as apoptosis and ferroptosis in DR was also revealed by hydroxysafflor yellow A(a single chalcone glycoside), maresin-1 (pro-resolving lipid mediator), amygdalin (natural cyanogenic glycoside) [160, 161]

We discovered that the injection of DOX increased the percentage of their immunological density and improved the immune expression of P53 and caspase-3

[1] Other side effects may include flushing (20.3%), injection site reactions (13.2%), headache (11.3%), vomiting (4.8%), cough (3.3%), fatigue (3.2%), hot flashes (2.7%), paresthesia (2.6%), dizziness (2.2%), and nasal congestion (2.1%)