The role of alterations of serotoninergic signaling in ASD was suggested by the observation that approximately 30% of individuals with ASD have high mean blood levels of 5-HT (124)
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Baseline comorbidities included distinct diagnosis of any of the following (yes, no): hypertension, hyperlipidemia, atrial fibrillation and flutter, deep vein thrombosis or pulmonary embolism, chronic heart failure, dementia, CKD stage, depression, anxiety, smoking, neuropathic pain, atherosclerotic cardiovascular disease (ASCVD), and additional weight or obesity-related conditions
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