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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

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World J Urol 2015

doi: 10.1073/pnas.85.10.3653

Vitamin B12 (also known as cobalamin) is used to make new cells, and is required to keep your bone marrow, nerves and blood cells healthy