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Sitagliptin and teneligliptin belong to the third class, forming interactions with the S1, S2, and S2 extensive subsites, which produce more extensive DPP4 inhibition [46]

NICE obesity guidance (CG189) recommends multicomponent interventions addressing diet, physical activity, and behaviour change as first-line management

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Lipopolysaccharide-mediated hepatic glutathione depletion and progressive mitochondrial damage in mice: protective effect of glutathione monoethyl ester